Open Call For Pilots

The application period is now closed. However, if you are still interested, please feel free to contact pilot@heuefs.eu. We will be happy to continue sharing information aligned with your interests, which may be helpful for future opportunities.

To support interested applicants, a variety of resources are already available, including training videos, templates, and essential documents. These materials are designed to help you better understand and navigate the pilot process. You can access them directly through the links provided below.

Access Training videos here.

CIP and Checklist, Informed Consent template and Contract and liability documents available here.


Early Feasibility Studies in European Union

ISO 14155:2020 defines Early Feasibility Studies (EFS) as limited clinical investigations designed to evaluate the initial clinical safety and performance of a medical device.

Conducted at an early stage, before the device design is finalised, EFS help collect critical insights on a device’s design, safety, functionality, and performance, especially when further nonclinical testing is unavailable or not informative.

Why EFS Matter

EFS play a key role in the evidence generation pathway, offering the potential to:

  • Increase investment attractiveness in the European medical technology landscape
  • Accelerate patient access to safe and innovative medical devices.
  • Strengthen the EU’s position as a hub of clinical excellence and innovation.

The Current Challenge

While EFS are permitted under the EU Medical Device Regulation (MDR), there is currently no harmonised pathway or specific framework to support their systematic adoption across the European Union (EU).

The HEU-EFS initiative aims to change this by developing a unified, structured approach to Early Feasibility Studies, enabling innovation and collaboration across Europe.

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